Would someone please explain the difference between the 2. I have an idea, but it is probably incorrect.

Also, I have a Ruger 10-22. Is it a rimfire and if so, can centerfire ammo be shot in it or is each type of ammo restricted to the type of weapon that only shoots the ammo. Thanks for any answer.

Ammo must be specific to the gun.

But above that, rimfire ammo fires by a firing pin strike to the RIM of the case...rim is hollow and there si priming compound inside the rim. BE3scasue of this need for a thin hollow rim, rimfies don't run at real high pressure.

Center fire fires by a strike to a replaceable seperate primer that is in the center of the case's head. Becasue of the seperate primer and solid head of the case, centerfires can be made to run at high pressure.

Thanks ribbonstone, I didn't know the specifics of what you posted, but I did have it right on the difference, just by the way it was named. I just needed the confirmation you provided to substantiate what I thought. Thank you.

In addition, rim fire cases are not reloadable. Center fire cases are reloadable, by pressing out the used primer and inserting a brand new one.

Another difference is that you can buy 500 rounds of .22LR ammo for around $10, while for most centerfire catridges you pay at least $10 for 20 rounds

You can do lots of .22 rimfire shooting with your Ruger 10-22 at very low cost! Also, there are lots of aftermarket parts that you can try that are designed specifically for your Ruger . Enjoy :p !